A 20 year old male is found to have weight loss and generalized lymphadenopathy. He has hypogammaglobulinemia with a normal distribution of immunoglobulin isotypes. Histologic exam of lymphoid tissue shows germinal center hyperplasia. A diagnosis of common variable immunodeficiency is made.
Which of the following is correct?
a. The patient likely had symptoms in childhood
b. At least one parent is also afflicted with the disease
c. The patient may develop recurrent bronchitis and chronic idiopathic diarrhea
d. The patient should receive the standard vaccine protocol