Type 1 diabetes
Polyuria, polydipsia, and weight loss associated with random plasma glucose of 200 mg/dl (11.1 mmol/L) or more.
Plasma glucose of 126 mg/dl (7.0 mmol/L) or more after a n overnight fast, documented on more than one occasion.
Ketonemia, ketonuria, or both.
Islet autoantibodies a re frequently present.
Type 2 diabetes
Many patients are over 40 years of age and obese.
Polyuria and polydipsia. Ketonuria and weight loss generally are uncommon at time of diagnosis. Candida vaginitis in women may be aninitial manifestation. Many patients have few or no symptoms.
Plasma glucose of 1 26 mg/dl or more after an overnight fa st o n more than one occasion. Two hours after 75 g oral glucose, diagnostic values are 200 mg/dl (11.1 m mol ) or more.
HbA1c 6.5% or more.
Hypertension, dyslipidemia, and atherosclerosis are often associated.